Protective Effect of Recombinant Interferon (IFN)-.ALPHA./.BETA. on MHV-2cc-induced Chronic Hepatitis in Athymic Nude Mice.
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چکیده
منابع مشابه
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Athymic nude mice recover from an infection with recombinant vaccinia virus (VV) encoding murine interleukin 2 (IL-2), but treatment with a mAb to IL-2 accentuated infection. Administration of a mAb against interferon gamma (IFN-gamma) to mice infected with the IL-2-encoding virus completely prevented the IL-2-induced mechanisms of recovery. Both asialo-GM1+ (NK) and asialo-GM1- (non-NK) cells ...
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The inflammatory response to herpes simplex virus infection of the cornea was studied in athymic nude (nu/nu) and heterozygote (nu/+) BALB/c mice. Although athymic mice were highly susceptible to HSV infection and died 13 to 17 days after corneal inoculation, they failed to develop necrotizing keratitis of the cornea. Heterozygote mice survived the initial virual infection, but many of these mi...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 1996
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.45.293